Evidence indicates that a melanoma prevention program using personalized genomic risk provision and genetic counseling can affect prevention behaviors, including reducing sunburns in adults with no melanoma history. This analysis evaluated its longer-term cost-effectiveness from an Australian health system perspective.
Hypertrophic cardiomyopathy (HCM) is the commonest genetic cardiomyopathy world-wide, affecting approximately 1 in 500 individuals. Current therapeutic interventions comprise lifestyle optimisation, medications, septal reduction therapies and rarely cardiac transplantation. Advances in our understanding of disease-causing genetic variants in HCM and their associated molecular mechanisms have [...]
Precision public health is an emerging and evolving field. Academic communities are divided regarding terminology and definitions, and what the scope, parameters and goals of precision public health should include. This protocol summarises the procedure for a scoping review which aims to identify and describe [...]
When the human genome was sequenced in the early 2000s, it promised a future of medicine tailored to your personal genetic makeup. Many millions of dollars have been spent researching genomic therapy, but it has saved a fraction of the lives of conventional – and [...]
One of the biggest challenges in medicine is how to offer hope without hype. Designing personalised treatments based on the science of the human genome will doubtless bring benefits, particularly for those with rare genetic conditions. But overpromoting the promise risks a tsunami of unwarranted [...]
