To our knowledge, this is the first methodological review of studies concerned with overdiagnosis in noncancer conditions. We identified 132 studies identifying or quantifying overdiagnosis of a wide range of noncancer conditions. We applied a novel framework that uses the concept of ‘‘Fair Umpires’’ to [...]
Thank you for the invitation to respond to a letter received about our article titled “Time to reflect on open-label placebos and their value for clinical practice.”Letter authors Ballou and Kube disagree with some of our criticisms of currently available research on open-label placebos (OLPs). [...]
The REFORM trial was a randomised, controlled non-inferiority trial in which participants were randomised to either remotely delivered physiotherapy or usual care . The assessor and statisticians were blinded. The protocol was published and the trial was prospectively registered. Participants were recruited from five public [...]
The linkage of primary care, hospital and other health registry data is a global goal, and a consent-based approach is often used. Understanding the attitudes of why participants take part is important, yet little is known about reasons for non-participation. The ATHENA COVID-19 feasibility study [...]
Corporations have been developing tactics to undermine independent science for decades. In the 1950s, on learning of the damaging effects of tobacco on health, the tobacco industry used campaigns of criticism to defend their products and the substantial revenue they were generating. Corporations could effectively [...]
In this article the Methods section of the Abstract was incorrectly given as “Economic costs were calculated alongside a randomised trial using standard cost analysis methodology from a societal perspective. Environmental impacts were calculated using a type of carbon footprinting methodology called process-based life cycle [...]
If a new clinical trial is to be justifiable both scientifically and ethically it should be designed in the light of an assessment of relevant previous research, ideally a systematic review. When its findings are reported, these should be set in the context of updated [...]
People often use infographics (also called visual or graphical abstracts) as a substitute for reading the full text of an article. This is a concern because most infographics do not present sufficient information to interpret the research appropriately and guide wise health decisions. The Reporting [...]
Although placebo-controlled trials are considered the gold standard for evaluating the efficacy of healthcare interventions, they can be perceived to be controversial and challenging to conduct for surgical treatments. The SUcceSS trial is the first placebo-controlled trial of lumbar decompression surgery for symptomatic lumbar canal [...]
Correction: Intensive Care Medicine https://doi.org/10.1007/s00134-023-07256-9 The original article has been corrected. The Authors apologize for the mistake. In the second paragraph of the second page, the first sentence “When using chemical sterilisation, such as ethyleneoxide gas or glutaraldehyde solution for bronchoscopes, reusable equipment will typically always [...]