Breast cancer (BC) mortality has declined over the past 30 years, reflecting improved screening, diagnosis and treatment. Over this period, the proportion of people with de novo metastatic BC (dnMBC) has remained relatively stable at approximately 6% of new BC, with cancer registries reporting incremental [...]
You order a computed tomography pulmonary angiogram (CTPA) for a patient with suspected pulmonary thromboembolism. The radiology report states that no pulmonary thromboembolism is seen but notes an unrelated lung nodule. What should you do with this incidental finding, or “incidentaloma”?
There is little evidence on the balance between potential benefits and harms of mammography screening in women 75 years and older. The aim of this systematic review was to synthesise the evidence on the outcomes of mammography screening in women aged 75 years and older. [...]
The purpose of this study is to summarize the literature regarding the performance of mammography-image based artificial intelligence (AI) algorithms, with and without additional clinical data, for future breast cancer risk prediction.
The present study examines the patterns of hospital and emergency department services in conjunction with both pre and post diagnostic periods of CT use, which has not been evaluated to date in adult patients with cancer. The cohort makes use of whole of population data [...]
Lung cancer screening (LCS) programs are being designed and implemented globally. Early data suggests that the psychosocial impacts of LCS are influenced by program factors, but evidence synthesis is needed. This systematic review aimed to elucidate the impact of service-level factors on psychosocial outcomes to [...]
Guidelines for prostate specific antigen (PSA) testing in Australia recommend that men at average risk of prostate cancer who have been informed of the benefits and harms, and who decide to undergo regular testing, should be offered testing every 2 years from 50 to 69 years. This [...]
High breast density on mammography is a well-established risk factor for a breast cancer diagnosis. There is interest in whether breast density might also predict how aggressive a breast cancer is, including the likelihood of causing death. If mammographic features at the time of cancer [...]
Primary care practitioners (PCPs) play a key role in cancer screening decisions for older adults (≥ 65 years), but recommendations vary by cancer type and jurisdiction. The purpose of this study is to examine the factors influencing PCPs’ recommendations for breast, cervical, prostate, and colorectal cancer [...]
Risk stratification of bowel cancer screening was acceptable to the informed public. Using data within the current system (age, sex and screening results) was considered an obvious next step and collecting additional data for lifestyle and/or genetic risk assessment was also preferable to age-based screening. [...]