The REFORM trial was a randomised, controlled non-inferiority trial in which participants were randomised to either remotely delivered physiotherapy or usual care . The assessor and statisticians were blinded. The protocol was published and the trial was prospectively registered. Participants were recruited from five public [...]
Controlled trials are the principal means of investigating the effects of therapeutic and prophylactic interventions. They can be designed to avoid biases, and so provide clear and reliable insights into 'what works' under ideal circumstances. Controlled trials can, however, also generate evidence to inform decisions [...]
The objective of this study is to evaluate an approach using automation and crowdsourcing to identify and classify randomized controlled trials (RCTs) for rheumatoid arthritis (RA) in a living systematic review (LSR). Records from a database search for RCTs in RA were screened first by [...]
Patients with kidney failure on hemodialysis (HD) experience considerable symptom burden and poor health-related quality of life (HRQoL). There is limited use of patient reported outcome measures (PROMs) in facility HD units to direct immediate care, with response rates in other studies between 36 to [...]
While controlled trials establish an intervention's effectiveness, poor intervention descriptions can obscure substantial variation. To address this problem, Kraiss and colleagues extend the systematic review process with several additional steps. Although important for clinical and policymaking in addiction, the considerable effort needed will be a [...]
Robust evidence regarding the benefits and harms of notifying Australian women when routine breast screening identifies that they have dense breasts is needed for informing future mammography population screening practice and policy. Objectives of this RCT are to assess the psychosocial and health services use [...]