Although clinicians acknowledged the limitations of the AMH test in predicting natural conception and would not offer the AMH test in the hypothetical scenario, many reported having used the test in their clinical practice for reasons not supported by the evidence (e.g. reproductive planning). Further, [...]
To the Editor: Good clinical decisions should weigh benefits against harms. The recent JAMA Insights article on gestational diabetes mellitus (GDM) focused on the potential benefits of increased detection and treatment of GDM and subsequent promotion of cardiovascular health.1 Unmentioned were the potential detrimental effects of overdiagnosis [...]
This study used a large longitudinal community-based population cohort to identify the fertility treatment pathways used by participants with and without PCOS and investigate whether any pathways were more likely to result in a birth. Our findings are in line with previous studies showing that [...]
We investigated differences in cumulative incidence of first distant recurrence following non-metastatic breast cancer over a time period when new adjuvant therapies became available in Australia. We conducted a health record linkage study of females with localized (T1-3N0) or regional (T4 or N+) breast cancer [...]
There is little evidence on the balance between potential benefits and harms of mammography screening in women 75 years and older. The aim of this systematic review was to synthesise the evidence on the outcomes of mammography screening in women aged 75 years and older. [...]
Objectives: To investigate the influence of preoperative breast MRI on mastectomy and reoperation rates in patients with pure ductal carcinoma in situ (DCIS). The MIPA observational study database (7245 patients) was searched for patients aged 18-80 years with pure unilateral DCIS diagnosed at core needle or [...]
In clinical practice, the co-existence of endometriosis and gastrointestinal symptoms is often observed. Using large-scale datasets, we report a genetic correlation between endometriosis and irritable bowel syndrome (IBS), peptic ulcer disease (PUD), gastro-esophageal reflux disease (GORD), and a combined GORD/PUD medicated (GPM) phenotype. Mendelian randomization analyses [...]
The purpose of our research was to explore how parents and their adolescent children make decisions about the human papillomavirus (HPV) vaccine, and to inform future interventions that aim to facilitate inclusive decision-making processes.
The prevalence of neonatal abstinence syndrome is increasing, but the number and quality of clinical practice guidelines available are unknown. This systematic review aimed to identify, appraise and evaluate clinical practice guidelines for neonatal abstinence syndrome. Methods: A systematic search of databases and the grey [...]
In 2014, the North American Menopause Society and the International Society for the Study of Women’s Sexual Health recommended using the term genitourinary syndrome of menopause (GSM) to cover a range of genital and urinary symptoms that might be experienced during and after menopause. The [...]